Pharmacogenomics An Introduction and Clinical Perspective

Goodman and Gilman's The Pharmacological Basis of Therapeutics

Pharmacogenomics An Introduction and Clinical Perspective

156.66 лв.

Publisher ‏ : ‎ McGraw-Hill Medical; New edition (16 Nov. 2012)
Language ‏ : ‎ English
Paperback ‏ : ‎ 288 pages
ISBN-10 ‏ : ‎ 0071741690
ISBN-13 ‏ : ‎ 978-0071741699
Dimensions ‏ : ‎ 21.59 x 1.65 x 27.64 cm

About the Author

Joseph S. Bertino Jr., Pharm.D. is an Associate Professor of Clinical Pharmacology in Medicine at the College of Physicians and Surgeons, Columbia University, New York, NY. His research interests are varied and include work with vaccines, antimicrobial pharmacokinetics and pharmacodynamics, treatment of hypertension, pharmacogenetics and pharmacogenomics. Dr. Bertino received the Pharm.D. degree from SUNY at Buffalo. He has published over 100 original research papers, review articles and book chapters. His publications have included work in the area of antimicrobial pharmacokinetics, pharmacodynamics and toxicity, drug-drug interactions, general clinical pharmacology, vaccine pharmacology and the application of pharmacogenetics to the drug development process.

Available on backorder

SKU: 978-0071741699 Categories: Genetics, Pharmacokinetics, Pharmacology, Pharmacology and pharmacotherapy Tag: no-bg

Description
Additional information

Pharmacogenomics An Introduction and Clinical Perspective

A COMPLETE INTRODUCTORY TEXT TO THE FIELD OF PHARMACOGENEMICS

A Doody's Core Title for 2017!

The only pharmacogenomics resource to feature a global author team comprised of PharmDs, MDs, PhDs and social scientists, Pharmacogenomics offers an essential, highly accessible survey of this dynamic discipline. You will find thorough coverage of all need-to-know topics, from individual molecules to systemic diseases, plus examination of the latest technologies that are constantly reshaping the field. Pharmacogenomics is cohesively organized into two sections, the first of which reviews basic aspects of pharmacogenomics, including ethics, regulatory, science, and drug metabolism, along with a "mini" course in molecular genetics and testing. The second section highlights the practical application of pharmacogenomics in cardiovascular medicine, immunology, neurology, and other specialties.

FEATURES

Important overview of general pharmacogenomics and pharmacogenetics concepts, including genetic variation in signal transduction and targets, plus a review of the genetic concepts of pharmacogenomics
Discussion of regulatory considerations in pharmacogenomics
Focus on the role of health care professionals along with a review of related privacy issues, as well as broader ethical, legal, and social considerations
In-depth chapters on drug metabolism and transporters
Practical, step-by-step guidance on public access to pharmacogenomic testing and patient counseling
Up-to-date coverage of non-genetic influences on pharmacogenomics
Emphasis on gene-drug interactions
Numerous tables and figures
Chapter-ending references
Concise learning objectives at the beginning of each chapter
Case studies to familiarize you with the clinical relevance of pharmacogenomics in each specialty

*****************************************************************************

Pharmacogenomics: An Introduction and Clinical Perspective is an important textbook that provides extensive information on pharmacogenomics and its role in modern medicine. Combining genetics and pharmacology, this discipline studies how genomic variation can influence an individual's response to drugs and how this information can be used for personalized treatment.

The textbook begins with an introduction to the basic concepts and principles of pharmacogenomics, including methods for analyzing genomic data and the relationship between genomic variation and pharmacodynamics and pharmacokinetics. Through clear and well-structured chapters, readers are introduced to the main genetic markers that can influence drug response, as well as methods for their study and interpretation.

Subsequent sections of the textbook focus on clinical applications of pharmacogenomics. Here, the various fields of medicine where personalized treatment can make a significant difference are considered, such as oncology, cardiology, psychiatry, and more. Through concrete clinical examples and cases, the textbook illustrates how pharmacogenomics can help optimize treatment strategies and improve patient outcomes.

Pharmacogenomics: An Introduction and Clinical Perspective also addresses ethical and regulatory issues related to the application of pharmacogenomics in clinical practice. These sections discuss issues such as the privacy of genetic information, the availability of tests for genomic variations, and the ethical challenges that arise when using genomic data to make medical decisions.

In addition, the textbook offers up-to-date information on advances in the field of pharmacogenomics, including new technologies for genomic data analysis and the development of personalized therapies. This aspect is essential because pharmacogenomics continues to be one of the key factors in the development of innovative and effective treatment methods.

In conclusion, Pharmacogenomics: An Introduction and Clinical Perspective is an extremely useful source of knowledge for anyone interested in the relationship between genetics and pharmacology. This textbook provides fundamental knowledge and practical guidance for the successful integration of pharmacogenomics into clinical practice, emphasizing the importance of personalized treatment to achieve better patient outcomes.