• • Offers unparalleled depth and up-to-date guidance on the full spectrum of allergy across the lifespan, with significant updates throughout.

• • Contains new chapters on Innate Lymphoid Cells, Systems Biology, and Treatment of Primary Immunodeficiency Diseases.

• • Discusses emerging topics such as epidemic thunderstorm asthma and precision medicine in allergic disorders.

• • Features more than 730 full-color illustrations, including many new cellular and molecular drawings of disease mechanisms.

• • Includes new Summary of Important Concepts boxes, plus new multiple-choice questions online with explanations and answers.

• • Features a new team of expert editors and more international contributors for a global perspective of this complex field.

• Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices.

By A Wesley Burks, MD, Professor and Chair, Pediatrics, Physician-in-Chief, North Carolina Children’s Hospital, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA; Stephen T Holgate, MD, DSc, FMedSci, MRC Professor of Immunopharmacology, Clinical and Experimental Sciences, Faculty of Medicine, Southampton University and General Hospital, Southampton, UK; Robyn E O’Hehir, FRACP, PhD, FRCPath, Professor and Director, Department of Allergy, Immunology and Respiratory Medicine, Alfred Hospital and Monash University, Melbourne Victoria, Australia ; Leonard B. Bacharier, MD, Professor of Pediatrics, Clinical Director, Division of Pediatric Allergy, Immunology and Pulmonary Medicine, Washington University School of Medicine in St Louis, Children’s Hospital, St Louis MO, USA; David H. Broide, Professor of Medicine; Gurjit K. Khurana Hershey, MD, PhD, Director, Division of Asthma Research; Co-Director, Office of Pediatric Clinical Fellowships; Professor, UC Department of Pediatrics, Cincinnati Children’s Hospital Medical Center, Cincinnati, OH and Stokes Peebles, MD, Associate Professor of Medicine