Biological effects of nanomaterials

The book is a summary of part of the world's experience in the production and application of nanoparticles for medical purposes at the moment. Methods of synthesis, as well as biological effects of the most common and studied materials are mainly considered. Attention is paid to the cytotoxic effects and the risk of indiscriminate use of nanoparticles. "The dose makes the poison," says Paracelsus, and this is entirely true of newly synthesized nanomaterials.
The book "Biological effects of nanomaterials" is intended for PhD students, specialists and everyone interested in the preparation, research and risks of new materials.

Iliana Ivanova is a long-time teacher at the Sofia University "St. Kliment Ohridski" and for more than 12 years has been engaged in researching the antimicrobial effect of nanomaterials - metal, metal-oxide and non-metal nanoparticles, single-layer and bulk coatings of one or more elements and compounds, organic and inorganic substances and nanocomposites.
Contents:

Introduction
History of nanomaterialsthem
Methods of obtaining nanomaterials
Nanoparticles as antimicrobial agents
Antimicrobial effects of nanoparticles

• Silver nanoparticles
• Combinations of silver nanoparticles with other substances
• Copper nanoparticles
• Titanium nanoparticles and TiO2 thin films
• Zinc nanoparticles
• Zinc titanate – ZnTiO3
• Iron oxide nanoparticles
• Aluminum nanoparticles
• Colloidal gold/nanogold
• Other metal nanoparticles
• Antimicrobial action of thin coatings

Nanocomposites with a non-metallic base

• Silicate derivatives
• Carbon nanotubes
• Graphene oxide and reduced graphene oxide
• Collagen composites
• Superhydrophobic coatings
• Surface topography and cell attachment
• Mechanisms of interaction of nanoparticles with bacteria
• Nanoparticle toxicity and bacterial gene expression
• Cytotoxic effect of biodegradables nanomaterials
• Ethical issues related to the safety of nanomaterialsthem
• Used literature
• Abbreviations used

Biological Effects of Nanomaterials is an exciting and up-to-date medical textbook that covers a vast field of science related to the study of biological interactions between nanomaterials and living systems. This textbook focuses on understanding the health implications of nanotechnology and provides students and medical professionals with a fascinating insight into this rapidly developing sector.

The first chapters of the textbook deal with the basic concepts of nanotechnology and the characteristics of nanomaterials. An explanation of their physicochemical properties and how they differ from larger particles is essential to understanding their biological effects.

The following chapters focus on the synthesis methods of nanomaterials and their applications in medicine. Nanoparticles, nanotubes, quantum dots, and other types of nanomaterials that are used in the diagnosis, treatment, and prevention of various diseases are examined.

The key part of the textbook deals with the biological effects of nanomaterials in the human organism. Mechanisms of interaction of nanoparticles with cells, tissues and organs are examined. Particular attention is paid to the possible toxic effects arising as a result of nanomaterials, as well as to the ways of transfer in the body and their accumulation.

The textbook also covers issues related to the safety of nanomaterials, including the potential risks and ethical challenges in this field. Students are encouraged to consider how modern scientific discoveries and technologies require responsible and ethical application, especially when it comes to human health.

One of the key aspects of the textbook is the combination of theoretical knowledge with practical applications. Examples from current research and clinical cases highlight real-world applications of nanomaterials in medicine and science. This learning method helps students connect theoretical concepts with contemporary challenges and opportunities in medical practice.

In conclusion, Biological Effects of Nanomaterials is a comprehensive and up-to-date guide that highlights the importance of carefully studying the biological aspects of nanomaterials. This textbook is ideal for students of medicine, dentistry and pharmacy, who seek a detailed understanding of the interaction between innovative nanotechnology and human health.