Dr. Georgi N. Chaldakov was born in 1940 in Burgas. Since 1970 he has been working in the Laboratory of Cell Biology, Department of Anatomy and Histology, Medical University - Varna.
With gene technology for embryonic stem cells you remove genes in mice and get knockout (KO) mice. This can provide valuable information about the functions of the protein encoded by the disrupted gene. For these discoveries, Mario Capecchi, Martin Evans and Oliver Smithies were awarded the Nobel Prize in 2007. physiology or medicine.
Look at these cuties – they were born at The Jackson Laboratory (JAX) in the US – the world’s largest center for breeding knockout mice. JAX has 7,000 different types of knockout mice and sends about three million of them annually to more than 20,000 researchers in 50-60 countries around the world.
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