THERAPEUTIC DIRECTORY OF MEDICAL ONCOLOGY
The Therapeutics Reference contains references to Medical Oncology (2018) by corresponding volume and page, in order to save volume and to avoid duplicating information in the two aids.
Preface…………………………………………………………………………………….7
Author team…………………………………………………………………………. 10
Systemic drug treatment of malignant neoplasms
on the head and neck……………………………………………………………….13
Carcinoma of the thyroid gland………………………………………………20
Lung cancer – systemic drug treatment…………………..24
Malignant mesothelioma……………………………………………………………… 45
Primary malignant tumors of the thymus……………………………….48
Systemic drug treatment of patients with early breast cancer.....51
Systemic drug treatment of patients with locally advanced and
metastatic breast cancer………………………………………….. 59
Esophageal carcinoma and carcinoma of the gastro-oesophageal junction…… 76
Stomach cancer………………………………………………………………………….84
Systemic drug treatment of primary malignant tumors
of the pancreas………………………………………………………………………….. 93
Hepatocellular carcinoma………………………………………………………….. 99
Carcinoma of the gallbladder and bile ducts…………………………… 101
Neuroendocrine tumors……………………………………………………105
Colorectal carcinoma and anal carcinoma…………………………………….. 110
Prostate cancer………………………………………………………………………… 127
Malignant tumors of the testicles…………………………………………133
Renal cell carcinoma……………………………………………………..142
Adrenocortical carcinoma, pheochromocytoma………………………………147
Bladder cancer………………………………………………………………149
Carcinoma of the cervix……………………………………………………. 157
Endometrial carcinoma…………………………………………………………162
Sarcomas of the uterine body……………………………………………………. 169
Trophoblastic tumors…………………………………………………………. 175
Malignant tumors of the vagina…………………………………………… 181
Malignant tumors of the vulva………………………………………………..183
Ovarian carcinoma…………………………………………………………………….185
Systemic drug treatment of malignant mesenchymal
tumors - osteosarcomas………………………………………………………………..195
Soft tissue sarcomas…………………………………………………….201
Gastrointestinal stromal tumors (GIS T) …………………………… 205
Primary and metastatic brain tumors……………………………….. 208
Systemic drug treatment of malignant tumors
with an unknown primary focus……………………………………………………213
Malignant skin tumors………………………………………………218
Toxicity of systemic drug therapy……………………………… 226
A. Hematological toxicity:
A.1. Anemias………………………………………………………………. 226
A.2. Neutropenia……………………………………………………………… 228
B. Non-hematological toxicity:
B.1. Gastrointestinal toxicity………………………………..231
B.2. Extravasates from cytotoxic medicinal products…. 244
Complications associated with ongoing treatment for solid
malignant tumors……………………………………………………………… 253
A. Hemorrhagic diathesis in oncological patients…………………. 253
B. Venous thromboembolism……………………………………………….. 270
C. Complications related to the application of immunotherapy……….. 294
Palliative and supportive drug treatment -
pain control in oncology…………………………………………. 299
Other administration-related toxicities and complications
of systemic drug therapy in solid tumors…………………..310
Prescribing biological drugs and their biosimilars
in oncology………………………………………………………………………….. 311
Children's malignant tumors……………………………………………………….315
Annex A…………………………………………………………………………..316
Appendix B………………………………………………………………………….. 317
Abbreviations used………………………………………………………………318
