Clinical Immunology - A Student's Guide
Prof. Elisaveta Naumova
Third Supplemented and Revised
Modern concepts of the structure and function of the immune system are presented in a synthesized form. Its protective role in protecting the body from the development of a number of diseases is considered.
The updated information provided is in the fields of fundamental and clinical immunology, related to immunodeficiency, autoimmune, infectious, allergic, malignant diseases, as well as organ, tissue and cell transplantation.
The modern ones are considered immunological studies and diagnostic approaches underlying the diagnosis and monitoring of these disease groups.
The basic principles of immunotherapy, based on the concept of modulating the immune system, with prophylactic and/or therapeutic goals, as well as the specific immunotherapy of immune system diseases and immune system-mediated diseases.
CONTENTS
Most commonly used abbreviations
1. IMMUNE SYSTEM
1.1. Primary and secondary lymphoid organs
1.2. Cells of the immune system
1.3. Antigens and antibodies
1.4. Complement system
1.5. Cytokine network
1.6. Major histocompatibility complex
2. IMMUNE RESPONSE
2.1. Basic principles, theories of the immune response
2.2. Innate (non-specific) immunity
2.3. Acquired (specific) immunity
2.4. Intercellular communication
2.5. Immune response in the gut
2.6. Age dynamics in the immune response
3. PRIMARY IMMUNE DEFICIENCIES
3.1. Overview
3.2. Predominant antibody deficiency
3.3. Immunodeficiencies affecting cellular and humoral immunity (combined T- and B-cell immunodeficiencies)
3.4. Combined immunodeficiencies with associated or syndromic features
3.5. Diseases of immune dysregulation
3.6. Congenital defects of phagocyte number or function
3.7. Defects in innate immunity
3.8. Complement deficiencies
3.9. Autoinflammatory diseases
3.10. Immunizations for immune deficiencies
3.11. Guidelines for the management of PID patients
4. SECONDARY IMMUNE DEFICIENCIES
5. INFECTIOUS IMMUNITY
5.1. Microorganisms and the immune system
5.2. Basic principles of the immune response against bacteria
5.3. Basic principles of the immune response against viruses
5.4. Basic principles of the immune response against fungi
5.5. Basic principles of the immune response against parasites
6. AUTOIMMUNITY AND AUTOIMMUNE DISEASES
6.1. Regulation of the immune response
6.2. Autoreactivity and autoimmunity
6.3. Autoimmune diseases
7. IMMUNOLOGICAL MECHANISMS OF ALLERGIC DISEASES. HYPERSENSITIVITY REACTIONS
7.1. Types of immune reactions
7.2. Allergic diseases
